Factors Associated With Activity Limitations in People With Rheumatoid Arthritis

OBJECTIVE. We evaluated factors contributing to activity limitations in people with rheumatoid arthritis (RA) according to the International Classification of Functioning, Disability and Health model.

METHOD. In a cross-sectional study, we measured five activity constructs in 81 people with RA.

RESULTS. Multiple regression analysis revealed the following results for the five constructs: (1) RA Activities (R² = .512) included handgrip strength, range of motion deficit, deformity, and mental health; (2) Upper-Limb Activities (R² = .473) included time since diagnosis, dexterity, handgrip strength, and range of motion deficit; (3) Timed Activities (R² = .320) included dexterity and work activities; (4) Physical Autonomy Activities (R² = .562) included range of motion deficit, vitality, pain, and functional classification; and (5) Physical Conditions for Activities (R² = .416) included functional classification and vitality.

CONCLUSION. Factors most associated with activity limitations were handgrip strength and hand range of motion deficits. Activity limitations in people with RA are multifactorial.