OBJECTIVE. We evaluated factors contributing to activity limitations in people with rheumatoid arthritis (RA) according to the International Classification of Functioning, Disability and Health model.

METHOD. In a cross-sectional study, we measured five activity constructs in 81 people with RA.

RESULTS. Multiple regression analysis revealed the following results for the five constructs: (1) RA Activities (R2 = .512) included handgrip strength, range of motion deficit, deformity, and mental health; (2) Upper-Limb Activities (R2 = .473) included time since diagnosis, dexterity, handgrip strength, and range of motion deficit; (3) Timed Activities (R2 = .320) included dexterity and work activities; (4) Physical Autonomy Activities (R2 = .562) included range of motion deficit, vitality, pain, and functional classification; and (5) Physical Conditions for Activities (R2 = .416) included functional classification and vitality.

CONCLUSION. Factors most associated with activity limitations were handgrip strength and hand range of motion deficits. Activity limitations in people with RA are multifactorial.

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