Systematic reviews of literature relevant to adults with Alzheimer’s disease and their families are important to the practice of occupational therapy. We describe the seven questions that served as the focus for systematic reviews of the effectiveness of occupational therapy interventions for adults with Alzheimer’s disease and their families. We include the background for the reviews; the process followed for each question, including search terms and search strategy; the databases searched; and the methods used to summarize and critically appraise the literature. The final number of articles included in each systematic review; a summary of the results; the strengths and limitations of the findings; and implications for practice, education, and research are presented for the six questions addressing interventions in the areas of occupation, perception, environment, activity demands, fall prevention, and caregiver strategies.

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