Systematic reviews of literature relevant to children and adolescents with difficulty processing and integrating sensory information are important to the practice of occupational therapy in this area. This article explains the five questions that were developed and served as the focus for these reviews: neuronal plasticity, subtyping, sensory integration and non–sensory integration occupational therapy interventions, and occupational performance for this population. Presented are the background for the reviews; the process followed for each question, including search terms and search strategy; the databases searched; and the methods used to summarize and critically appraise the literature. The final number of articles included in each systematic review, a summary of the results of the review, the strengths and limitations of the review, and implications for practice, education, and research are described.

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