The purpose of this article is to describe parental adherence to home treatment programs. A qualitative exploratory study with six parents and eight occupational therapists who used the brushing and compression technique (Wilbarger Protocol) was conducted. Participants were interviewed one or two times, exploring their experiences in adhering to the protocol. Data analysis focused on facilitators and hindrances to parental adherence and on occupational therapists’ strategies used to encourage it. Parents identified their children’s responses to brushing, its perceived efficacy, and interaction of the protocol with family daily schedules, as factors influencing their adherence. Occupational therapists identified only family daily schedules as influencing parental adherence. The findings are discussed in the context of the ecocultural theory of family accommodations.