The purpose of this study was to document variation in affective responses to different types of traditional occupational therapy activities. Each of 45 subjects (24 psychiatric inpatients and 21 matched control subjects) participated in a series of four activities: leather lacing, working with clay, filing, and exercycling. Immediately following each activity, each subject completed the Affective Self-Report Checklist designed to elicit affective responses. In addition, each of the activity sessions was professionally videotaped and later rated for affective responses by trained observers. The data analysis revealed no significant differences in affective responses to activities between groups. However, with the groups combined, significant differences were found in affective responses on 6 of the 15 scales of the checklist, with clay and filing the pair of activities that differed most. These findings are a necessary first step in the collection of baseline data regarding responses to activities.